Robert P. Sticca, MD
Lab Director
J. David Goossens, BA
Research Specialist
Phone: (701) 777-3282
Fax: (701) 777-2609
Email: jgoossens@medicine.nodak.edu
J. David Goossens is a Research Specialist in the Department of Surgery’s Research Laboratory at the University of North Dakota School of Medicine and Health Sciences (UNDSMHS). He received his Bachelors of Arts degree in Biology from Saint John’s University in Collegeville, Minnesota.
David joined the staff of the UNDSMHS in June 2003, and the Department of Surgery in January 2005. He has previously participated in Parkinsons Disease research before joining the Department of Surgery.
Tonya Murphy, BS
Research Assistant
Phone: (701) 777-3282
Fax: (701) 777-2609
Email: tmurphy@medicine.nodak.edu
Tonya Murphy is a Research Assistant in the Department of Surgery’s Research Laboratory at the University of North Dakota School of Medicine and Health Sciences (UNDSMHS). She received her Bachelors of Science degree in Recreation from the University of North Dakota in 1988.
Tonya joined the staff of the Department of Surgery in February 2008. Since 1986 she has been involved with research at the University of North Dakota with various positions on campus including the Human Nutrition Research Center, and the departments of Biology and Pharmacology, Physiology and Therapeutics. Previous research projects have been in the areas of trace element effect on learning and memory, endocrinology, DNA sequencing, and Alzheimer’s Disease.
Timothy A. Bigelow, PhD
Assistant Professor
Department of Electrical Engineering
Phone: (701) 777-3374
Fax: (701) 777-2609
Email: timothybigelow@mail.und.nodak.edu
Timothy A. Bigelow graduated summa cum laude from Colorado State University in December 1998 with a B.S. in Electrical Engineering and a minor in Mathematics. He then completed his M.S. and Ph.D. degrees at the University of Illinois at Urbana-Champaign while working in the Bioacoustics Research Laboratory under Dr. William D. O’Brien, Jr. While pursuing his graduate education, Dr. Bigelow was awarded a National Defense Science and Engineering Fellowship and a Beckman Institute Graduate Fellowship. After completing his education, he was a Visiting Assistant Professor in the Electrical and Computer Engineering Department at the University of Illinois at Urbana-Champaign for a year.
Currently, Dr. Bigelow is an Assistant Professor in Electrical Engineering at the University of North Dakota. His research interests focus on improving the diagnostic and therapeutic effectiveness of medical ultrasound. Specifically he focuses on quantifying the physical properties of tissue using backscattered ultrasound signals, applying ultrasound enhanced drug delivery to specific medical problems, and exploring ultrasound induced bioeffects for both ultrasound safety and ultrasound therapy applications.
1. Sticca RP, Palmer ML. Polyp of the Appendix. New England Journal of Medicine. 329(23), 1993
2. McAlhany JC, Taylor SM, Sticca RP, Ashmore JD, Hanover TM. Long Term Follow-up with Roux-en-Y Gastrojejunostomy for the Treatment of Gastric Disease. Annals of Surgery. 219(5), 451-457, 1994.
3. Sticca RP, Spellman J, Perez-Mesa C, Karakousis CP. Advanced Neurofibromatosis of the Lower Extremity Requiring Hemipelvectomy. Surgical Rounds. 18(9),367-372, 1995.
4. Sticca RP, Rodriguez-Bigas M, Penetrante RB, Petrelli NJ. Curative Resection for Stage I Rectal Cancer: Natural History, Prognostic Factors and Recurrence Patterns. Cancer Investigation. 14 (5), 491-497, 1996.
5. Sticca, RP, Weatherford DA, McAlhany JC. Carcinoma of the Ampulla of Vater: A Community Hospital Experience. The American Surgeon. 62(3), 197-202, 1996.
6. Taylor SM, Weatherford DA, Carsten CG, Sticca RP, Langan EM. The Routine Use of Implantable Subcutaneous Infusion Ports: An Outcome Analysis in an Oncology Population. American College of Surgeons Surgical Forum. 47, 657-659, 1996.
7. Jones GB, Kilgore MW, Pollenz RS, Li A, Mathews JE, Wright JM, Huber RS, Tate PL, Price TL, Sticca RP. Target Directed Enediyne Prodrugs: hER and AhR Degradation by a Synthetic Oxo-enediyne. Bio-organic & Medicinal Chemistry Letters. 6 (16), 1971-76, 1996.
8. Gouldman JW, Sticca RP, Rippon MD, McAlhany JC. Laparoscopic Cholecystectomy in Pregnancy. The American Surgeon. 64(1), 93-98, 1998.
9. Chen WY, Ramamoorthy P, Chen NY, Sticca RP, Wagner TE. A Human Prolactin Antagonist, hPRL-G129, Inhibits Breast Cancer Cell Proliferation through Induction of Apoptosis. Clinical Cancer Research. 5(11), 3583-3593, 1999.
10. Wei Y, Li J, Chen WY, YuX, Sticca RP, Wagner TE. Enhanced Transgene Expression and Effective in Vivo Anti-Tumor Immune Responses Initiated by Dendritic Progenitors Transfected with a Non-Viral T7 Vector Expressing A Model Tumor Antigen. Journal of Immunotherapy. 23(1), 75-82, 2000.
11. Cataldo L, Chen NY, Yuan Q, Li W, Ramamoorthy P, Wagner TE, Sticca RP, Chen WY. Inhibition of Oncogene STAT3 Phosphorylation by a Prolactin Antagonist, hPRL-G129R, in T-47D Human Breast Cancer Cells. International Journal of Oncology. 17, 1179-1185, 2000.
12. Ramamoorthy P, Sticca R, Wagner TE, Chen WY. In Vitro Studies of a Prolactin Antagonist, hPRL-G129R in Human Breast Cancer Cells. International Journal of Oncology. 18, 25-32, 2001.
13. Holmes LM, Li J, Sticca RP, Wagner TE, Wei Y. A Rapid, Novel Strategy to Induce Tumor Cell Specific Cytotoxic T Lymphocyte Responses Using Instant Dendritomas. Journal of Immunotherapy. 24(2), 122-129, 2001.
14. Schwab DP, Blackhurst DW, Sticca RP. Operative Acute Small Bowel Obstruction – Admitting Service Impacts Outcome. The American Surgeon. 67, 1034-1040, 2001.
15. Yousef AM, Davis RA, Sticca RP, Berger SH. Structural Analysis of cDNA Encoding Thymidylate Synthase in Hepatic Metastases of Human Colorectal Tumors. International Journal of Colorectal Disease. 16, 318-325, 2001.
16. Jones GB, Wright JM, Hynd G, Wyatt JK, Warner PM, Huber RS, Li A, Kilgore MW, Sticca RP, Pollenz RS. Oxa-enediynes: Probing the Electronic and Stereoelectronic Contributions to the Bergman Cycloaromatization. Journal of Organic Chemistry. 67(16), 5727-32, 2002.
17. Sticca RP, Dach BW. Rationale for Hyperthermia with Intraoperative Intraperitoneal Chemotherapy Agents. Surgical Oncology Clinics of North America. 12(3), 689-701, 2003.
18. Patel AP, Harris JB, Lokey JS, Sticca RP, McGill ES, Arrillaga A, Miller RS, Kopelman TR. Current Management of Common Bile Duct Stones in a Teaching Community Hospital. American Surgeon. 69(7), 555-61, 2003.
19. Foltz P, Warvrin C, Sticca R. Heated Intraoperative Intraperitoneal Chemotherapy- The Challenges of Bringing Chemotherapy into Surgery. Association of Operating Registered Nurses Journal. 80(6), 1054-63, 2004.
20. Wei Y, Sticca R, Holmes LM, Burgin KE, Li J, Williamson J, Evans L, Smith SJ, Stephenson JJ, Wagner TE. Dendritoma Vaccination Combined with Low Dose Interleukin-2 in Metastatic Melanoma Patients Induced Immunologic and Clinical Responses. Submitted, Clinical Cancer Research.
21. Anderson DR, Seeger GR, Barnstuble BB, Sticca RP, Sahmoun AE. Assessment of Hysterectomy Route Selection in a Community Hospital: A Retrospective Analysis. Submitted, European Journal of Obstetrics and Gynecology and Reproductive Biology.
22. Sticca RP, Usatii A, Brown M. Vaginal Evisceration. Manuscript in Preparation.
23. Sticca RP, Syribeys PJ, West L. Liposarcoma of the Spermatic Cord: Implications for the General Surgeon. Manuscript in Preparation.
Surgical residents are required to participate in a yearly clinical research project in conjunction with a faculty mentor. The results of these projects are presented each year at the Surgery Resident Research Colloquium with awards given to the two best research projects. Many of these clinical research projects culminate in local, regional or national presentations with subsequent peer review publications.
